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Powers (2000-2004)
- **Synopsis for Powers (2000-2004)** In a world brimming with extraordinary powers, Detective Christian Walker stands as the lone guardian of justice on the city's gritty streets. While heroes...
- Last issue: Powers (2000) Issue #37

Power Pack (2000)
- The Power Family has relocated to Seattle, where the siblings encounter fresh obstacles in the form of school bullies, adolescent romance, and a whole new institution. From navigating classes to...
- Last issue: Power Pack (2000) Issue #4

Planetary/The Authority: Ruling the World (2000-)
- **Planetary/The Authority: Ruling the World** The enigmatic Planetary team delves into the secrets surrounding the superhuman Authority. However, their investigation is disrupted when the Authority...
- Last issue: Planetary/The Authority: Ruling the World Full

Pedro and Me (2000-)
- Pedro and Me (2000) is a graphic novel series that explores the complex and heartwarming relationship between a young boy named Judd and his family's Guatemalan gardener, Pedro. In the...
- Last issue: Pedro and Me TPB (Part 2)

Parts Unknown: Hostile Takeover (2000-)
- In the gripping conclusion of "Parts Unknown: Hostile Takeover," chaos erupts as a deadly conflict reaches its peak. The fate of the nation hangs in the balance as the ruthless terrorist...
- Last issue: Parts Unknown: Hostile Takeover Full

Overkill: Witchblade/Aliens/Darkness/Predator (2000-2001)
- In the first thrilling crossover between Top Cow and Dark Horse, chaos descends upon New York City. Aliens swarm the metropolis, seeking a breeding ground for their deadly offspring. Jackie Estacado,...
- Last issue: Overkill: Witchblade/Aliens/Darkness/Predator Issue #2

Outlaw Nation (2000-2002)
- **Outlaw Nation** (2000-2002) From the pages of Desperado Publishing comes the complete collection of "Outlaw Nation," a thrilling adventure series from writer Jamie Delano and artist Goran...
- Last issue: Outlaw Nation Issue #19

Orion (2000-2002)
- **Orion: A Cosmic Odyssey of Identity and Vengeance (2000-2002)** Prepare for an exhilarating journey with Orion, Kirby's enigmatic New God and JLA member, as he embarks on a quest to unravel...
- Last issue: Orion Issue #25

Only the End of the World Again (2000-)
- **Only the End of the World Again (2000)** In the eerie coastal town of Innsmouth, mysteries lurk within the shadows. Lawrence Talbot, an insurance adjuster, finds himself at the heart of a chilling...
- Last issue: Only the End of the World Again Full

Objective Five (2000-2001)
- **Synopsis:** OBJECTIVE FIVE exposes a chilling secret: biological weapons of mass destruction, once denied by governments, now exist. The CDC's covert Objective Five team, led by Lark, Alexis,...
- Last issue: Objective Five Issue #6